CRSEXP022

=Researcher= Cuepil Choi =Objective= To see if 4-chlorobenzaldehyde and methanol will create acetals without any catalysts. =Procedure= An excess amount of methanol was added to 4-chlorobenzaldehyde in a 1 dram vial. The mixture was allowed to sit overnight HNMR spectra were taken. =Results= [|HNMR 1] - ([|integration sheet]) 1225 min (overnight) 4:1 aldehyde to hemiacetal 6:1 aldehyde to acetal [|HNMR 2] ([|integration sheet]) 1232 min (same as HNMR 1, retaken for better phasing; same ratios as above) =Discussion= The acetals may have only been created because of the trace amount of 4-chlorobenzoic acid. However, the trace amount of acid is unlikely to have a big impact on the reaction. A further study of the effect of 4-chlorobenzoic acid will need to be done. =Conclusion= HNMR spectrum shows a trace of 4-chlorobenzoic acid in the 8.63-8.66 ppm range. Mixture shows acetal formation of 6:1 aldehyde to acetal overnight at 25 C. =Log=

2013-09-03
17:12 0.0462 g of 4-chlorobenzaldehyde added to 1 dram vial 17:13 0.4114 g of methanol added to 1 dram vial

2013-09-04
13:38 HNMR 1 taken of vial 1 13:45 HNMR 2 taken of vial 1