CRSEXP045

Scheme


acetic anhydride in RA methanol in RA methyl acetate in RA acetic acid in RA esterification in RA

Researcher
Kayla Gogarty [|Reaction Attempts]

Objective
The purpose of this experiment is to determine the results of a reaction of acetic anhydride and methanol, using HNMR to analyze the results.

Results
Time: 2 hours [|CRSEXP045A-NMR1] pure acetic anhydride [|CRSEXP045B-NMR1] pure methanol [|CRSEXP045C-NMR1] half by volume acetic anhydride and half by volume methanol [|CRSEXP045D-NMR1] one drop acetic anhydride in excess methanol [|CRSEXP045E-NMR1] one drop methanol in excess acetic anhydride

Time: 18 and a half hours [|CRSEXP045A-NMR2] pure acetic anhydride [|CRSEXP045B-NMR2] pure methanol [|CRSEXP045C-NMR2] half by volume acetic anhydride and half by volume methanol [|CRSEXP045D-NMR2] one drop acetic anhydride in excess methanol [|Mole Fractions] [|CRSEXP045E-NMR2] one drop methanol in excess acetic anhydride [|Mole Fractions]

Discussion
Based on the HNMR spectra, the peaks for the product are bigger after 18 and a half hours than after 2 hours. Therefore, the reaction was not complete after 2 hours and the reaction occurs slowly without a catalyst. Based on literature searches, the reaction is typically performed with an inorganic catalyst with heating. performed the reaction without a catalyst, but heating was required. Even though the reaction performed slowly without a catalyst and without heating, the reaction still occurred within 18 and a half hours. However, complete conversion was not achieved.


 * CRSEXP045D-NMR2**


 * CRSEXP045E-NMR1**

Log
15:00-Prepared five mixtures CRSEXP043A- pure acetic anhydride CRSEXP043B- pure methanol CRSEXP043C- Half by volume acetic anhydride and half by volume methanol CRSEXP043D- one drop acetic anhydride in excess methanol CRSEXP043E- one drop methanol in excess acetic anhydride 17:10-HNMR of the five mixtures were taken 16 scans, 1second relaxation delay, 45 degree pulse angle, CDCl3 as solvent
 * 14-04-09**

10:15-HNMR of the five mixtures were taken 16 scans, 1second relaxation delay, 45 degree pulse angle, CDCl3 as solvent
 * 14-04-10**